Article
Confirmation of association of the GABRA2 gene with alcohol dependence by subtype-specific analysis.
Psychiatric genetics - 1 Feb 2006
Fehr Christoph, Sander Thomas, Tadic Andre, Lenzen Kirsten P, Anghelescu Ion, Klawe Christoph, Dahmen Norbert, Schmidt Lutz G, Szegedi Armin
Abstract excerpt
OBJECTIVES: Three recent studies revealed a haplotypic association of alcohol dependence with the gene encoding the alpha2 subunit of the gamma-aminobutyric acid type A (GABAA) receptor (GABRA2). The present study examined whether variation of the GABRA2 gene confers susceptibility to different subtypes of alcohol dependence in the German population. METHODS: A total of 257 German alcohol-dependent patients and...
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