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Article

GABRG1 and GABRA2 as independent predictors for alcoholism in two populations.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Apr 2009

Enoch Mary-Anne, Hodgkinson Colin A, Yuan Qiaoping, Albaugh Bernard, Virkkunen Matti, Goldman David

Abstract excerpt

The chromosome 4 cluster of GABA(A) receptor genes is predominantly expressed in the brain reward circuitry and this chromosomal region has been implicated in linkage scans for alcoholism. Variation in one chromosome 4 gene, GABRA2, has been robustly associated with alcohol use disorders (AUD) although no functional locus has been identified. As HapMap data reveal moderate long-distance linkage disequilibrium...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 18818659
DOI: 10.1038/npp.2008.171
PMCID: PMC2656604

Genes

GABRA2
GABRG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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