Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Multistage sampling for genetic studies.

Annual review of genomics and human genetics - 1 Jan 2007

Elston Robert C, Lin Danyu, Zheng Gang

Abstract excerpt

In the past, to study Mendelian diseases, segregating families have been carefully ascertained for segregation analysis, followed by collecting extended multiplex families for linkage analysis. This would then be followed by association studies, using independent case-control samples and/or additional family data. Recently, for complex diseases, the initial sampling has been for a genome-wide linkage analysis,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic Linkage
Share to Genetics, Population
Share to Models, Theoretical

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Polymorphism, Single Nucleotide

Share to Research Design

Share to Sampling Studies

Source

Identifiers

PMID: 17506660
DOI: 10.1146/annurev.genom.8.080706.092357

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Multistage sampling for genetic studies.PMID 17506660Read ↗

Multistage sampling for disease family registries.Semantic proximity Read ↗

Prioritize and select SNPs for association studies with multi-stage designs.Semantic proximity Read ↗

Multi-stage sampling in genetic epidemiology.Semantic proximity Read ↗

Two-Stage sampling designs for gene association studies.Semantic proximity Read ↗

Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studies.Semantic proximity Read ↗

Two-phase stratified sampling designs for regional sequencing.Semantic proximity Read ↗

Study designs for genome-wide association studies.Semantic proximity Read ↗

Design Considerations for Genetic Linkage and Association Studies.Semantic proximity Read ↗

Including sampling and phenotyping costs into the optimization of two stage designs for genomewide association studies.Semantic proximity Read ↗

Probability that a two-stage genome-wide association study will detect a disease-associated snp and implications for multistage designs.Semantic proximity Read ↗

Optimal DNA pooling-based two-stage designs in case-control association studies.Semantic proximity Read ↗

Evaluating statistical significance in two-stage genomewide association studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.