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Article

Multistage sampling for disease family registries.

Journal of the National Cancer Institute. Monographs - 1 Jan 1999

Siegmund K D, Whittemore A S, Thomas D C

Abstract excerpt

BACKGROUND: The objectives of a family-based disease registry range from characterizing measured genetic factors and gene-environment interaction effects to detecting novel susceptibility genes. Gathering complete information on exposure and disease status in all family members for a sample of affected subjects (probands) to address these diverse objectives would be prohibitively expensive. METHODS: Multistage...

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PMID: 10854485
DOI: 10.1093/oxfordjournals.jncimonographs.a024225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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