Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of the C3435T polymorphism of the multidrug resistance 1 gene on the severity of inflammatory bowel disease in Iranian Azeri Turks.

Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association - 1 Jan 2000

Bonyadi Mortaza J, Gerami Sousan M, Somi Mohammad H, Khoshbaten Manouchehr

Abstract excerpt

BACKGROUND/AIM: Multidrug resistance 1 (MDR1) gene encodes for P-glycoprotein (P-gp), a transmembrane efflux pump transferring both exogenous and endogenous substrate from the cells. In the human gastrointestinal tract, P-gp is found in high concentrations on the epithelial cells of the colon and small intestine. It is hypothesized that the expression level of MDR1 gene is related to susceptibility of both forms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily B, Member 1
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Inflammatory Bowel Diseases

Share to Severity of Illness Index

Share to Surveys and Questionnaires

Share to Turkey

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 23828747
DOI: 10.4103/1319-3767.114515
PMCID: PMC3745659

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of the C3435T polymorphism of the multidrug resistance 1 gene on the severity of inflammatory bowel disease in Iranian Azeri Turks.PMID 23828747Read ↗

The frequency of C3435T MDR1 gene polymorphism in Iranian patients with ulcerative colitis.Semantic proximity Read ↗

MDR1 C3435T polymorphism and inflammatory bowel disease risk: a meta-analysis.Semantic proximity Read ↗

MDR1 polymorphisms are associated with inflammatory bowel disease in a cohort of Croatian IBD patients.Semantic proximity Read ↗

Multidrug resistance 1 gene in inflammatory bowel disease: a meta-analysis.Semantic proximity Read ↗

[Is C3435T polymorphism of MDR1 related to inflammatory bowel disease or colorectal cancer in Korean?].Semantic proximity Read ↗

Genetic Polymorphisms of Multidrug Resistance Gene-1 (MDR1/ABCB1) and Glutathione S-Transferase Gene and the Risk of Inflammatory Bowel Disease among Moroccan Patients.Semantic proximity Read ↗

Multidrug resistance 1 gene polymorphism and susceptibility to inflammatory bowel disease.Semantic proximity Read ↗

Association between the C3435T MDR1 gene polymorphism and susceptibility for ulcerative colitis.Semantic proximity Read ↗

C3435T Polymorphism of the ABCB1/MDR1 gene encoding P-glycoprotein in patients with inflammatory bowel disease in a Polish populationSemantic proximity Read ↗

Multidrug resistance 1 gene polymorphisms may determine Crohn's disease behavior in patients from Rio de Janeiro.Semantic proximity Read ↗

Pharmacogenetics of drug metabolizing enzyme: thiopurine methyl transferase phenotypes and multidrug resistance 1 gene polymorphism in inflammatory bowel disease.Semantic proximity Read ↗

Is there evidence to claim or deny association between variants of the multidrug resistance gene (MDR1 or ABCB1) and inflammatory bowel disease?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.