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Article

C3435T Polymorphism of the ABCB1 Gene in Polish Patients with Inflammatory Bowel Disease: A Case-Control and Meta-Analysis Study.

Genes - 15 Sept 2021

Petryszyn Paweł, Dudkowiak Robert, Gruca Agnieszka, Jaźwińska-Tarnawska Ewa, Ekk-Cierniakowski Paweł, Poniewierka Elżbieta, Wiela-Hojeńska Anna, Głowacka Krystyna

Abstract excerpt

P-glycoprotein encoded by the ABCB1 gene constitutes a molecular barrier in the small and large bowel epithelium, and its different expression may influence susceptibility to inflammatory bowel disease (IBD). We aimed to assess the contribution of the C3435T polymorphism to disease risk in the Polish population. A total of 100 patients (50 Crohn's disease (CD), 50 ulcerative colitis (UC)) and 100 healthy controls...

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Identifiers

PMID: 34573401
DOI: 10.3390/genes12091419
PMCID: PMC8465101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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