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Article

ATM missense variant P1054R predisposes to prostate cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology - 1 Jun 2007

Meyer Andreas, Wilhelm Bettina, Dörk Thilo, Bremer Michael, Baumann Rolf, Karstens Johann Hinrich, Machtens Stefan

Abstract excerpt

BACKGROUND: Prostate cancer is associated with defective DNA strand break repair after DNA damage leading to genetic instability and prostate cancer progression. The ATM (ataxia-telangiectasia mutated) gene product is known to play an important role in cell cycle regulation and maintenance of genomic integrity. We investigated whether the prevalence of the ATM missense substitution P1054R is increased in a...

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Source

Identifiers

PMID: 17502119
DOI: 10.1016/j.radonc.2007.04.029

Genes

ATM

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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