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Article

Single nucleotide polymorphisms in DNA repair genes as risk factors associated to prostate cancer progression.

BMC medical genetics - 24 Dec 2014

Henríquez-Hernández Luis Alberto, Valenciano Almudena, Foro-Arnalot Palmira, Álvarez-Cubero María Jesús, Cozar José Manuel, Suárez-Novo José Francisco, Castells-Esteve Manel, Fernández-Gonzalo Pablo, De-Paula-Carranza Belén, Ferrer Montse, Guedea Ferrán, Sancho-Pardo Gemma, Craven-Bartle Jordi, Ortiz-Gordillo María José, Cabrera-Roldán Patricia, Herrera-Ramos Estefanía, Rodríguez-Gallego Carlos, Rodríguez-Melcón Juan Ignacio, Lara Pedro C

Abstract excerpt

BACKGROUND: Besides serum levels of PSA, there is a lack of prostate cancer specific biomarkers. It is need to develop new biological markers associated with the tumor behavior which would be valuable to better individualize treatment. The aim of this study was to elucidate the relationship between single nucleotide polymorphisms (SNPs) in genes involved in DNA repair and prostate cancer progression. METHODS: A...

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Source

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Identifiers

PMID: 25540025
DOI: 10.1186/s12881-014-0143-0
PMCID: PMC4316399

Genes

ATM
ERCC1
ERCC2
LIG4
XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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