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Article

Single-nucleotide polymorphisms studied for associations with urinary toxicity from (125)I prostate brachytherapy implants.

Brachytherapy - 1 Jan 2000

Usmani Nawaid, Leong Nelson, Martell Kevin, Lan Lanna, Ghosh Sunita, Pervez Nadeem, Pedersen John, Yee Don, Murtha Albert, Amanie John, Sloboda Ron, Murray David, Parliament Matthew

Abstract excerpt

PURPOSE: To identify clinical, dosimetric, and genetic factors that are associated with late urinary toxicity after a (125)I prostate brachytherapy implant. METHODS AND MATERIALS: Genomic DNA from 296 men treated with (125)I prostate brachytherapy monotherapy was extracted from saliva samples for this study. A retrospective database was compiled including clinical, dosimetric, and toxicity data for this cohort of...

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Age Distribution
Aged
Alberta
DNA-Binding Proteins
Iodine Radioisotopes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Prostatic Neoplasms

X-ray Repair Cross Complementing Protein 1

Source

Identifiers

PMID: 24656733
DOI: 10.1016/j.brachy.2014.02.002

Genes

ATM
ERCC2
GSTA1
GSTP1
LIG4
MSH6
RAD51
SOD2
XRCC1
XRCC3

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