Article
An intracellular motif of P2X(3) receptors is required for functional cross-talk with GABA(A) receptors in nociceptive DRG neurons.
Journal of neurochemistry - 1 Aug 2007
Toulmé Estelle, Blais Dominique, Léger Claire, Landry Marc, Garret Maurice, Séguéla Philippe, Boué-Grabot Eric
Abstract excerpt
Functional cross-talk between structurally unrelated P2X ATP receptors and members of the 'cys-loop' receptor-channel superfamily represents a recently-discovered mechanism for rapid modulation of information processing. The extent and the mechanism of the inhibitory cross-talks between these two classes of ionotropic receptors remain poorly understood, however. Both ionic and molecular coupling were proposed to...
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