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Article

[Single nucleotide polymorphism in the promoter region of asparagine synthetase and its impact on the gene expression].

Zhongguo shi yan xue ye xue za zhi - 1 Apr 2007

Luo Chang-Ying, Li Ben-Shang, Tie Li-Jun, Gu Long-Jun

Abstract excerpt

High expression of cellular asparagine synthetase (AS) is a causative factor for the resistance of leukemic cell to L-asparaginase therapy. This study was aimed to find single nucleotide polymorphism (SNPs) in the promotor region of asparagine synthetase (AS) gene and to determine if these SNPs have influence on the transcriptional activity of AS promotor. The DNA sequences of AS promoter (pAS) from 82 leukemic...

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Share to Leukemia, Myeloid, Acute
Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Promoter Regions, Genetic

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PMID: 17493332

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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