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Article

ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia.

Blood - 24 Nov 2011

Rousseau Julie, Gagné Vincent, Labuda Malgorzata, Beaubois Cyrielle, Sinnett Daniel, Laverdière Caroline, Moghrabi Albert, Sallan Stephen E, Silverman Lewis B, Neuberg Donna, Kutok Jeffery L, Krajinovic Maja

Abstract excerpt

Asparaginase is a standard and critical component in the therapy of childhood acute lymphoblastic leukemia. Asparagine synthetase (ASNS) and the basic region leucine zipper activating transcription factor 5 (ATF5) and arginosuccinate synthase 1 (ASS1) have been shown to mediate the antileukemic e...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21972289
DOI: 10.1182/blood-2011-05-355560
PMCID: PMC3342855

Genes

ATF5
ASNS
ASS1
EFS

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21972289-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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ATF5 polymorphisms influence ATF function and response to treatment in children with childhood acute lymphoblastic leukemia.PMID 21972289Read ↗

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