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Article

Regulation of asparagine synthetase gene expression by amino acid starvation.

Molecular and cellular biology - 1 Dec 1991

Gong S S, Guerrini L, Basilico C

Abstract excerpt

We have studied the regulation of expression of the asparagine synthetase (AS) gene in ts11 cells, a mutant of BHK hamster cells which encodes a temperature-sensitive AS and therefore does not produce endogenous asparagine at 39.5 degrees C. Incubation of ts11 cells at the nonpermissive temperatu...

Topics

Amino Acids
Animals
Asparagine
Aspartate-Ammonia Ligase
Base Sequence
Cells, Cultured
Cricetinae
DNA
Down-Regulation
Gene Expression Regulation, Enzymologic
Humans
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Protein Biosynthesis

RNA, Messenger

Source

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Identifiers

PMID: 1682798
DOI: 10.1128/mcb.11.12.6059-6066.1991
PMCID: PMC361776

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1682798-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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