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Article

Novel mutations of the extraneuronal monoamine transporter gene in children and adolescents with obsessive-compulsive disorder.

The international journal of neuropsychopharmacology - 1 Feb 2008

Lazar Andreas, Walitza Susanne, Jetter Alexander, Gerlach Manfred, Warnke Andreas, Herpertz-Dahlmann Beate, Gründemann Dirk, Grimberg Gundula, Schulz Eberhard, Remschmidt Helmut, Wewetzer Christoph, Schömig Edgar

Abstract excerpt

Obsessive-compulsive disorder (OCD) is a disease of complex aetiology with a marked genetic component. Impact of the serotonergic system has been reported but the contribution of additional transmitter systems to the pathogenesis seems likely. The extraneuronal monoamine transporter, EMT (SLC22A3), is implicated in non-neuronal termination of noradrenergic signalling in the central nervous system and a candidate...

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PMID: 17477885
DOI: 10.1017/S1461145707007742

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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