Pilot study on HTR2A promoter polymorphism, -1438G/A (rs6311) and a nearby copy number variation showed association with onset and severity in early onset obsessive-compulsive disorder.

doi:10.1007/s00702-011-0699-1

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Pilot study on HTR2A promoter polymorphism, -1438G/A (rs6311) and a nearby copy number variation showed association with onset and severity in early onset obsessive-compulsive disorder.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Apr 2012

Walitza Susanne, Bové Daniel Sabanés, Romanos Marcel, Renner Tobias, Held Leonhard, Simons Michael, Wewetzer Christoph, Fleischhaker Christian, Remschmidt Helmut, Warnke Andreas, Grünblatt Edna

Abstract excerpt

A previous study showed that a single nucleotide polymorphism (SNP), -1438G/A (rs6311), found in the transcriptional control region of the gene that encodes the serotonin-receptor 2A (HTR2A) was associated with obsessive-compulsive disorder (OCD) in a sample of children and adolescents. In this study, we reanalyzed the association of this SNP with OCD in an enlarged population of 136 cases (55 previous + 81 new...

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PMID: 21874579
DOI: 10.1007/s00702-011-0699-1

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HTR2A

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