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Article

Trio study and meta-analysis support the association of genetic variation at the serotonin transporter with early-onset obsessive-compulsive disorder.

Neuroscience letters - 19 Sept 2014

Walitza Susanne, Marinova Zoya, Grünblatt Edna, Lazic Stanley E, Remschmidt Helmut, Vloet Timo D, Wendland Jens R

Abstract excerpt

Despite compelling evidence for major genetic contributions to the etiology of obsessive-compulsive disorder (OCD), few genetic variants have been consistently associated with this debilitating illness. Molecular genetic studies in children and adolescents with OCD are of particular interest, since early onset of the disease has been observed to be associated with increased familiality. We replicate here for the...

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Identifiers

PMID: 25093702
DOI: 10.1016/j.neulet.2014.07.038
PMCID: PMC4167890

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