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Article

Serotonin transporter missense mutation associated with a complex neuropsychiatric phenotype.

Molecular psychiatry - 1 Nov 2003

Ozaki N, Goldman D, Kaye W H, Plotnicov K, Greenberg B D, Lappalainen J, Rudnick G, Murphy D L

Abstract excerpt

Two common serotonin transporter (SERT) untranslated region gene variants have been intensively studied, but remain inconclusively linked to depression and other neuropsychiatric disorders. We now report an uncommon coding region SERT mutation, Ile425Val, in two unrelated families with OCD and other serotonin-related disorders. Six of the seven family members with this mutation had OCD (n=5) or...

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Identifiers

PMID: 14593431
DOI: 10.1038/sj.mp.4001365

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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