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Article

Characterization of SLITRK1 variation in obsessive-compulsive disorder.

PloS one - 1 Jan 2013

Ozomaro Uzoezi, Cai Guiqing, Kajiwara Yuji, Yoon Seungtai, Makarov Vladimir, Delorme Richard, Betancur Catalina, Ruhrmann Stephan, Falkai Peter, Grabe Hans Jörgen, Maier Wolfgang, Wagner Michael, Lennertz Leonhard, Moessner Rainald, Murphy Dennis L, Buxbaum Joseph D, Züchner Stephan, Grice Dorothy E

Abstract excerpt

Obsessive compulsive disorder (OCD) is a syndrome characterized by recurrent and intrusive thoughts and ritualistic behaviors or mental acts that a person feels compelled to perform. Twin studies, family studies, and segregation analyses provide compelling evidence that OCD has a strong genetic component. The SLITRK1 gene encodes a developmentally regulated stimulator of neurite outgrowth and previous studies...

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Source

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Identifiers

PMID: 23990902
DOI: 10.1371/journal.pone.0070376
PMCID: PMC3749144

Genes

SLITRK1

Variants

Provenance

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