Article
Genes expressed by both mesangial cells and bone marrow-derived cells underlie genetic susceptibility to crescentic glomerulonephritis in the rat.
Journal of the American Society of Nephrology : JASN - 1 Jun 2007
Smith Jennifer, Lai Ping-Chin, Behmoaras Jacques, Roufosse Candice, Bhangal Gurjeet, McDaid John P, Aitman Timothy, Tam Frederick W K, Pusey Charles D, Cook H Terence
Abstract excerpt
The Wistar-Kyoto (WKY) rat shows marked susceptibility to crescentic glomerulonephritis. In the model of nephrotoxic nephritis (NTN) that is induced by a small dose of nephrotoxic globulin, WKY rats developed crescents in 80 +/- 2% of glomeruli at day 10, whereas no crescents were seen in Lewis r...
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