Article
A Th1 response is essential for induction of crescentic glomerulonephritis in mice.
Kidney & blood pressure research - 1 Jan 1999
Schatzmann U, Haas C, Le Hir M
Abstract excerpt
Crescentic glomerulonephritis can be induced in rodents by injection of heterologous antibodies against the glomerular basement membrane. There is evidence that glomerular inflammation in that model represents a delayed-type hypersensitivity response to the heterologous immunoglobulin, whereas the antibody response is not important. The aim of the present study was to test this hypothesis. Delayed-type...
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