Article
Monoclonal antibody against rat podocyte-derived macrophagic cells reacts with crescent-forming cells in an experimental model.
Nephrology (Carlton, Vic.) - 1 Oct 2003
Orikasa Michiaki, Iwanaga Toshihiko, Kawachi Hiroshi, Oyanagi Akihisa, Li Ping, Su Qian, Kobayashi Hideo, Nakayama Hitoshi, Kikuchi Hiroshi, Shimizu Fujio
Abstract excerpt
The origin of crescent-forming cells in crescentic glomerulonephritis has not been clarified in spite of the application of monoclonal antibodies (mAbs) against glomerular epithelial cells or monocytes/macrophages. This study was undertaken to characterize the cellular composition of crescents using a new marker, mAb OS-3, produced against macrophagic cells derived from podocytes in normal rat glomerular culture....
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