Article
Searching genomes for ribozymes and riboswitches.
Genome biology - 1 Jan 2007
Hammann Christian, Westhof Eric
Abstract excerpt
New regulatory RNAs with complex structures have recently been discovered, among them the first catalytic riboswitch, a gene-regulatory RNA sequence with catalytic activity. Here we discuss some of the experimental approaches and theoretical difficulties attached to the identification of new ribozymes in genomes.
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