Article
RNA structure. Ribozyme evolution at the crossroads.
Science (New York, N.Y.) - 21 Jul 2000
Joyce G F
Abstract excerpt
Molecules that have similar sequences usually adopt the same structures and have the same functions. In his Perspective, Joyce explains that this is not always the case. In a remarkable study (Schultes and Bartel), an RNA sequence has been designed that can adopt two different structures, each with a different catalytic function. Joyce details how this study sheds light on the evolution of enzymes.
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