Article

Genome-Wide Identification of Stable RNA Secondary Structures Across Multiple Organisms Using Chemical Probing Data: Insights into Short Structural Motifs and RNA-Targeting Therapeutics

2024-10-09

Abstract excerpt

<h4>ABSTRACT</h4> Small molecules targeting specific RNA binding sites, including stable and transient RNA structures, are emerging as effective pharmacological approaches for modulating gene expression. However, little is understood about how stable RNA secondary structures are shared across organisms, an important factor in controlling drug selectivity. In this study, I provide an analytical pipeline named RNA...

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Literature Corpus work: 0312b260-d85f-5273-a3ce-5e5dcff5c15a
DOI: 10.1101/2024.10.08.617329

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