Article
The common Y402H variant in complement factor H gene is not associated with susceptibility to myocardial infarction and its related risk factors.
Clinical science (London, England : 1979) - 1 Aug 2007
Stark Klaus, Neureuther Katharina, Sedlacek Kamil, Hengstenberg Wibke, Fischer Marcus, Baessler Andrea, Wiedmann Silke, Jeron Andreas, Holmer Stephan, Erdmann Jeanette, Schunkert Heribert, Hengstenberg Christian
Abstract excerpt
Recently, the genetic variant Y402H in the CFH (complement factor H) gene was associated with an increased risk for MI (myocardial infarction) in a prospective Caucasian cohort. In another nested case-control study, however, the CFH-Y402H variant did not carry susceptibility to MI. The aim of the present study was to test for an association between the CFH-Y402H variant and MI in a large case-control sample with...
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