Article
Lack of association between complement factor H polymorphisms and coronary artery disease or myocardial infarction.
Journal of molecular medicine (Berlin, Germany) - 1 Jul 2007
Nicaud Viviane, Francomme Carole, Ruidavets Jean-Bernard, Luc Gérald, Arveiler Dominique, Kee Frank, Evans Alun, Morrison Caroline, Blankenberg Stefan, Cambien François, Tiret Laurence
Abstract excerpt
Complement factor H (CFH) plays a critical role in the protection of host cells and tissues from damage by complement activation and has been suggested to protect against the progression of atherosclerosis. A polymorphism in the CFH gene, Y402H, known to be strongly associated with age-related macular degeneration, has been analyzed in relation to coronary artery disease (CAD) in several studies with conflicting...
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