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Article

Complement factor H variant Y402H is not a risk factor for preeclampsia in the Finnish population.

Hypertension in pregnancy - 1 Jan 2008

Kaare M, Seitsonen S, Jarvela I, Meri S, Laivuori H

Abstract excerpt

OBJECTIVE: Variations in complement factor H, which down-regulates the activity of the alternative complement pathway, have been associated with different vascular disorders. Here we examine whether factor H variation is involved in the etiology of preeclampsia. METHODS: We studied 110 women with preeclampsia and 99 controls for complement factor H variations by sequencing. RESULTS: No significant differences in...

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PMID: 19003634
DOI: 10.1080/10641950801955691

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Complement factor H variant Y402H is not a risk factor for preeclampsia in the Finnish population.PMID 19003634Read ↗

Identification of complement factor H variants that predispose to pre-eclampsia: A genetic and functional study.Semantic proximity Read ↗

Complement factor H Y402H gene polymorphism, C-reactive protein, and risk of incident myocardial infarction, ischaemic stroke, and venous thromboembolism: a nested case-control study.Semantic proximity Read ↗

The common Y402H variant in complement factor H gene is not associated with susceptibility to myocardial infarction and its related risk factors.Semantic proximity Read ↗

Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study.Semantic proximity Read ↗

Complement factor H Y402H decreases cardiovascular disease risk in patients with familial hypercholesterolaemia.Semantic proximity Read ↗

Complement factor H (Y402H) polymorphism and risk of coronary heart disease in US men and women.Semantic proximity Read ↗

The molecular basis of familial hemolytic uremic syndrome: mutation analysis of factor H gene reveals a hot spot in short consensus repeat 20.Semantic proximity Read ↗

Genetic analysis of human complement factor H polymorphisms.Semantic proximity Read ↗

Lack of association between complement factor H polymorphisms and coronary artery disease or myocardial infarction.Semantic proximity Read ↗

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