Article
Common polymorphisms in the cannabinoid CB2 receptor gene (CNR2) are not associated with myocardial infarction and cardiovascular risk factors.
International journal of molecular medicine - 1 Aug 2008
Reinhard Wibke, Stark Klaus, Neureuther Katharina, Sedlacek Kamil, Fischer Marcus, Baessler Andrea, Weber Stefan, Kaess Bernhard, Wiedmann Silke, Erdmann Jeanette, Lieb Wolfgang, Jeron Andreas, Riegger Guenter, Hengstenberg Christian
Abstract excerpt
Myocardial infarction (MI) is a complex disease. Multiple genes and their interaction with various environmental factors influence the pathogenesis of MI that is thought to be tightly regulated by inflammatory pathways. Recent progress in genetic analysis includes the use of large-scale genome-wide association studies that have proven to be powerful tools even in the analysis of multifactorial phenotypes....
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