A common polymorphism in the complement factor H gene is associated with increased risk of myocardial infarction: the Rotterdam Study.

doi:10.1016/j.jacc.2005.11.076

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Article

A common polymorphism in the complement factor H gene is associated with increased risk of myocardial infarction: the Rotterdam Study.

Journal of the American College of Cardiology - 18 Apr 2006

Kardys Isabella, Klaver Caroline C W, Despriet Dominiek D G, Bergen Arthur A B, Uitterlinden André G, Hofman Albert, Oostra Ben A, Van Duijn Cornelia M, de Jong Paulus T V M, Witteman Jacqueline C M

Abstract excerpt

OBJECTIVES: This study was designed to investigate the association between a common polymorphism (Tyr402His, rs1061170) in the complement factor H (CFH) gene and risk of coronary heart disease. BACKGROUND: The evidence that inflammation is an important mechanism in atherogenesis is growing. C-reactive protein (CRP), complement factors, and complement regulatory factors have all been linked to coronary heart...

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PMID: 16630992
DOI: 10.1016/j.jacc.2005.11.076

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A common polymorphism in the complement factor H gene is associated with increased risk of myocardial infarction: the Rotterdam Study.PMID 16630992Read ↗

Usefulness of combining complement factor H and C-reactive protein genetic profiles for predicting myocardial infarction (from the Rotterdam Study).Semantic proximity Read ↗

Genetic variation in complement factor H and risk of coronary heart disease: eight new studies and a meta-analysis of around 48,000 individuals.Semantic proximity Read ↗

Complement factor H (Y402H) polymorphism and risk of coronary heart disease in US men and women.Semantic proximity Read ↗

Complement factor H Y402H decreases cardiovascular disease risk in patients with familial hypercholesterolaemia.Semantic proximity Read ↗

Association of the complement factor H Y402H polymorphism with cardiovascular disease is dependent upon hypertension status: The ARIC study.Semantic proximity Read ↗

Complement factor H Y402H polymorphism, plasma concentration and risk of coronary artery disease.Semantic proximity Read ↗

Complement factor H 402His variant confers an increased mortality risk in Finnish nonagenarians: the Vitality 90+ study.Semantic proximity Read ↗

Complement factor H Y402H gene polymorphism and coronary heart disease susceptibility: a meta-analysis.Semantic proximity Read ↗

Complement Factor H polymorphism Y402H associates with inflammation, visual acuity, and cardiovascular mortality in the elderly population at large.Semantic proximity Read ↗

Complement factor H Y402H gene polymorphism, C-reactive protein, and risk of incident myocardial infarction, ischaemic stroke, and venous thromboembolism: a nested case-control study.Semantic proximity Read ↗

Complement factor H Y402H polymorphism results in diminishing CD4+ T cells and increasing C-reactive protein in plasma.Semantic proximity Read ↗

The common Y402H variant in complement factor H gene is not associated with susceptibility to myocardial infarction and its related risk factors.Semantic proximity Read ↗

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