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Article

The kinesin related motor protein, Eg5, is essential for maintenance of pre-implantation embryogenesis.

Biochemical and biophysical research communications - 8 Jun 2007

Castillo Andrew, Justice Monica J

Abstract excerpt

Eg5 is a plus end directed kinesin related motor protein (KRP) previously shown to be involved in the assembly and maintenance of the mitotic spindle. KRPs are molecular motors capable of generating forces upon microtubules (MTs) in dividing cells and driving structural rearrangements necessary in the developing spindle. In vitro experiments demonstrate that loss of Eg5 results in cell cycle arrest and defective...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17449012
DOI: 10.1016/j.bbrc.2007.04.021
PMCID: PMC2760081

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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