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Article

Fbxo30 Regulates Mammopoiesis by Targeting the Bipolar Mitotic Kinesin Eg5.

Cell reports - 3 May 2016

Liu Yan, Wang Yin, Du Zhanwen, Yan Xiaoli, Zheng Pan, Liu Yang

Abstract excerpt

Fbxo30 is an orphan member of the F-box protein family with no known substrate or function. Here we report that, while Fbxo30(-/-) mice exhibit normal development, growth, lifespan, and fertility, the females fail to nurture their offspring as a result of defective mammopoiesis. Mass spectrometry analysis of Fbxo30-associated proteins revealed that Fbxo30 specifically interacts with the bipolar spindle kinesin...

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Identifiers

PMID: 27117404
DOI: 10.1016/j.celrep.2016.03.083
PMCID: PMC4856546

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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