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Article

Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions.

Nature communications - 8 Apr 2020

Tedeschi Antonio, Almagro Jorge, Renshaw Matthew J, Messal Hendrik A, Behrens Axel, Petronczki Mark

Abstract excerpt

In mammalian cell lines, the endosomal sorting complex required for transport (ESCRT)-III mediates abscission, the process that physically separates daughter cells and completes cell division. Cep55 protein is regarded as the master regulator of abscission, because it recruits ESCRT-III to the midbody (MB), the site of abscission. However, the importance of this mechanism in a mammalian organism has never been...

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Identifiers

PMID: 32269212
DOI: 10.1038/s41467-020-15359-w
PMCID: PMC7142149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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