Significance of genetic abnormalities of p53 protein in Slovenian patients with gastric carcinoma.

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Article

Significance of genetic abnormalities of p53 protein in Slovenian patients with gastric carcinoma.

Croatian medical journal - 1 Apr 2007

Juvan Robert, Hudler Petra, Gazvoda Barbara, Repse Stanislav, Bracko Matej, Komel Radovan

Abstract excerpt

AIM: To analyze genetic alterations of p53 gene in Slovenian gastric cancer patients and to compare these alterations with clinicopathological parameters in order to assess the value of p53 as a prognostic factor. METHODS: We analyzed the samples from 230 Slovenian patients with gastric cancer, collected between 1983 and 2001. p53 expression was evaluated immunohistochemically with DO-7 monoclonal antibody. In...

Topics

Female
Genes, p53
Humans
Loss of Heterozygosity
Male
Microsatellite Instability
Middle Aged
Mutation
Neoplasm Staging
Prognosis
Sex Distribution
Slovenia
Stomach Neoplasms
Survival Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 17436385
PMCID: PMC2080507

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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