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Article

p53 immunostaining cannot be used to predict TP53 mutations in gastric cancer: results from a large Central European cohort.

Human pathology - 1 Nov 2020

Schoop Isabelle, Maleki Saffiyeh Saboor, Behrens Hans-Michael, Krüger Sandra, Haag Jochen, Röcken Christoph

Abstract excerpt

Four molecular subgroups of gastric cancer (GC) have been proposed, ie, Epstein-Barr virus (EBV)-positive, microsatellite instable, chromosomal instable (CIN), and genomically stable GC. Based on the complex relationship between chromosomal instability and TP53 mutational status, we hypothesized that the typical clinicopathological characteristics caused by chromosomal instability are correlated with the p53...

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PMID: 32971129
DOI: 10.1016/j.humpath.2020.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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