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Article

p53 alterations in gastric carcinoma: a study of 56 primary tumors and 204 nodal metastases.

Cancer genetics and cytogenetics - 1 Jul 1994

Seruca R, David L, Castedo S, Veiga I, Børresen A L, Sobrinho-Simões M

Abstract excerpt

We have looked for LOH, mutation, and expression of p53 in a series of 56 primary gastric carcinomas, using Southern blotting, constant denaturant gel electrophoresis (CDGE), direct sequencing, and immunohistochemistry. Two hundred-four lymph node metastases from 36 of these cases were also studied by immunohistochemistry. Loss of constitutional heterozygosity for the p53 locus was detected in five of 16...

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Identifiers

PMID: 8039163
DOI: 10.1016/0165-4608(94)90214-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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