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Article

Heparanase gene haplotype (CGC) is associated with stage of disease in patients with ovarian carcinoma.

Cancer science - 1 Jun 2007

Ralph Shirley, Brenchley Paul E C, Summers Angela, Rosa Daniela D, Swindell Ric, Jayson Gordon C

Abstract excerpt

Heparanase (HSPE-1) and vascular endothelial growth factor (VEGF), proangiogenic growth factors, play important roles in the metastatic biology of ovarian cancer. The aim of the present study was to test for association between single nucleotide polymorphisms (SNPs) in HSPE-1 and VEGF and outcome in ovarian cancer. A mutational analysis was performed on the coding sequence of the HSPE-1 gene to define...

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Identifiers

PMID: 17419711
DOI: 10.1111/j.1349-7006.2007.00461.x
PMCID: PMC11158553

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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