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Article

Polymorphisms and a haplotype in heparanase gene associations with the progression and prognosis of gastric cancer in a northern Chinese population.

PloS one - 1 Jan 2012

Li Ai-Lin, Song Yong-Xi, Wang Zhen-Ning, Gao Peng, Miao Yuan, Zhu Jin-Liang, Yue Zhen-Yu, Xu Hui-Mian

Abstract excerpt

BACKGROUND: Human heparanase plays an important role in cancer development and single nucleotide polymorphisms (SNPs) in the heparanase gene (HPSE) have been shown to be correlated with gastric cancer. The present study examined the associations between individual SNPs or haplotypes in HPSE and susceptibility, clinicopathological parameters and prognosis of gastric cancer in a large sample of the Han population...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22276173
DOI: 10.1371/journal.pone.0030277
PMCID: PMC3262795

Genes

HPSE

Provenance

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