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Article

Association of heparanase gene (HPSE-1) single nucleotide polymorphisms with gastric cancer.

Journal of surgical oncology - 1 Jul 2010

Yue Zhenyu, Song Yongxi, Wang Zhenning, Luo Yang, Jiang Li, Xing Lili, Xu Huimian, Zhang Xue

Abstract excerpt

BACKGROUND: Heparanase activity plays a decisive role in biological processes associated with remodeling of the extracellular matrix (e.g., cancer metastasis, angiogenesis, and inflammation). Heparanase gene overexpression has been associated with advanced stage and poor survival in several cancers. We investigated the potential association between single nucleotide polymorphisms (SNPs) of the HPSE-1 gene, tumor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20578081
DOI: 10.1002/jso.21584

Genes

HPSE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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