Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Heparanase polymorphisms: influence on incidence of hepatic sinusoidal obstruction syndrome in children undergoing allogeneic hematopoietic stem cell transplantation.

Journal of cancer research and clinical oncology - 1 May 2015

Seifert Claudia, Wittig Susan, Arndt Clemens, Gruhn Bernd

Abstract excerpt

PURPOSE: Sinusoidal obstruction syndrome (SOS) is a life-threatening early complication after hematopoietic stem cell transplantation (HSCT), and until now, examinations about the influence of genetic risk factors are extremely rare. The purpose of this study was to identify an association between heparanase (HPSE) single nucleotide polymorphisms (SNPs) and SOS in children undergoing allogeneic HSCT. METHODS: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glucuronidase
Share to Hematopoietic Stem Cell Transplantation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Incidence

Share to Infant, Newborn

Share to Kaplan-Meier Estimate

Share to Time Factors

Share to Transplantation Conditioning

Share to Transplantation, Homologous

Source

Identifiers

PMID: 25335953
DOI: 10.1007/s00432-014-1857-2

Genes

HPSE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Heparanase polymorphisms: influence on incidence of hepatic sinusoidal obstruction syndrome in children undergoing allogeneic hematopoietic stem cell transplantation.PMID 25335953Read ↗

Heparanase wildtype is associated with a reduced incidence of transplant-associated systemic vasculopathies.Semantic proximity Read ↗

Genetic Susceptibility to Hepatic Sinusoidal Obstruction Syndrome in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation.Semantic proximity Read ↗

Discrepancy between recipient and donor rs4364254 heparanase single nucleotide polymorphism impacts graft-versus-host disease after allogeneic stem cell transplant.Semantic proximity Read ↗

Genetic variations in the heparanase gene (HPSE) associate with increased risk of GVHD following allogeneic stem cell transplantation: effect of discrepancy between recipients and donors.Semantic proximity Read ↗

Association of CTH variant with sinusoidal obstruction syndrome in children receiving intravenous busulfan and cyclophosphamide before hematopoietic stem cell transplantation.Semantic proximity Read ↗

Association of heparanase gene (HPSE) single nucleotide polymorphisms with hematological malignancies.Semantic proximity Read ↗

Modification of heparanase gene expression in response to conditioning and LPS treatment: strong correlation to rs4693608 SNP.Semantic proximity Read ↗

Genomic screening and complications of hematopoietic stem cell transplantation: has the time come?Semantic proximity Read ↗

SAT-344-YI Long-term outcome of sinusoidal obstruction syndrome secondary to hematopoietic stem cell transplantationSemantic proximity Read ↗

The HPSE Gene Insulator-A Novel Regulatory Element That Affects Heparanase Expression, Stem Cell Mobilization, and the Risk of Acute Graft versus Host Disease.Semantic proximity Read ↗

Association of CYP2C19 Single Nucleotide Polymorphism With Hemorrhagic Cystitis After Pediatric Allogeneic Hematopoietic Stem Cell Transplantation.Semantic proximity Read ↗

Diagnosis and Treatment of VOD/SOS After Allogeneic Hematopoietic Stem Cell TransplantationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.