Article
Reassessing HPSE in Ovarian Cancer: Beneficial After All?
2026-02-19
Abstract excerpt
<title>Abstract</title> <p> Background Heparanase (HPSE) uniquely cleaves heparan sulfate, the main component of the outer layer of endothelial cell plasma membranes, promoting tumour invasion and dissemination. However, it can also enhance tumour immune surveillance and clearance. HPSE’s versatility extends to pro-thrombotic properties, such as the promotion of tissue factor release. Interestingly, elevated HP...
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Identifiers and source
- Literature Corpus work
- 0878d854-ce7f-5dd9-bf47-d37644c7d2e7
- DOI
- 10.21203/rs.3.rs-8799366/v1