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HLA-G 3′ untranslated region variants +3187G/G, +3196G/G and +3035T define diametrical clinical status and disease outcome in epithelial ovarian cancer

1 Apr 2019

Abstract excerpt

Expression of the non-classical human leukocyte antigen-G (HLA-G) promotes cancer progression in various malignancies including epithelial ovarian cancer (EOC). As single nucleotide polymorphisms (SNPs) in the HLA-G 3' untranslated region (UTR) regulate HLA-G expression, we investigated HLA-G 3'UTR haplotypes arranged by SNPs in healthy controls (n = 75) and primary EOC patients (n = 79) and determined soluble...

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Share to Ovarian cancer diagnosis and treatment
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30932005
DOI: 10.1038/s41598-019-41900-z

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