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Wild type and H43Y variant of human TRIM5alpha show similar anti-human immunodeficiency virus type 1 activity both in vivo and in vitro.

Immunogenetics - 1 Jun 2007

Nakayama Emi E, Carpentier Wassila, Costagliola Dominique, Shioda Tatsuo, Iwamoto Aikichi, Debre Patrice, Yoshimura Kazuhisa, Autran Brigitte, Matsushita Shuzo, Theodorou Ioannis

Abstract excerpt

Polymorphisms in human genes have been shown to affect the rate of disease progression to acquired immune deficiency syndrome in human immunodeficiency virus type 1 (HIV-1)-infected individuals. Recently, tripartite motif 5alpha (TRIM5alpha) was identified as a factor that confers resistance to HIV-1 infection in Old World monkey cells. Subsequently, Sawyer et al. (Curr Biol 16:95-100, 2006) reported a single...

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PMID: 17406861
DOI: 10.1007/s00251-007-0217-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Wild type and H43Y variant of human TRIM5alpha show similar anti-human immunodeficiency virus type 1 activity both in vivo and in vitro.PMID 17406861Read ↗

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