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Article

Genetic polymorphism of cytochrome P450 and methods for its determination.

Prague medical report - 1 Jan 2006

Buzková H, Pechandová K, Slanar O, Perlík F

Abstract excerpt

The majority of human P450 dependent drug metabolism is carried out by polymorphic enzymes which can alter plasma concentration of the pharmacological active substance followed by an enhanced or suppressed pharmacological effect. The response of individual patients to drugs can be affected by variations in DNA sequence mainly by single nucleotide polymorphisms (SNPs). Knowledge of functionally important SNPs...

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Identifiers

PMID: 17402551

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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