Article
Pharmacogenetics of cytochrome P450 (CYP) in the elderly.
Ageing research reviews - 1 Oct 2010
Seripa Davide, Pilotto Andrea, Panza Francesco, Matera Maria Giovanna, Pilotto Alberto
Abstract excerpt
The genetics of cytochrome P450 (CYP) is a very active area of multidisciplinary research, overlapping the interest of medicine, biology and pharmacology, being the CYP enzyme system responsible for the metabolism of more than 80% of the commercially available drugs. Variations in CYP encoding genes are responsible for inter-individual differences in CYP production or function, with severe clinical consequences...
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