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Article

Riboflavin activated by ultraviolet A1 irradiation induces oxidative DNA damage-mediated mutations inhibited by vitamin C.

Proceedings of the National Academy of Sciences of the United States of America - 3 Apr 2007

Besaratinia Ahmad, Kim Sang-In, Bates Steven E, Pfeifer Gerd P

Abstract excerpt

An increasingly popular theory ascribes UVA (>320-400 nm) carcinogenicity to the ability of this wavelength to trigger intracellular photosensitization reactions, thereby giving rise to promutagenic oxidative DNA damage. We have tested this theory both at the genomic and nucleotide resolution level in mouse embryonic fibroblasts carrying the lambda phage cII transgene. We have also tested the hypothesis that...

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Identifiers

PMID: 17389394
DOI: 10.1073/pnas.0610534104
PMCID: PMC1851598

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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