Article
Increased mutant frequency by carbon black, but not quartz, in the lacZ and cII transgenes of muta mouse lung epithelial cells.
Environmental and molecular mutagenesis - 1 Jul 2007
Jacobsen Nicklas Raun, Saber Anne Thoustrup, White Paul, Møller Peter, Pojana Giulio, Vogel Ulla, Loft Steffen, Gingerich John, Soper Lynda, Douglas George R, Wallin Håkan
Abstract excerpt
Carbon black and quartz are relatively inert solid particulate materials that are carcinogenic in laboratory animals. Quartz is a human carcinogen, whereas data on carbon black are contradictory, and there are few data on mammalian mutagenesis. We determined the mutant frequency following eight repeated 72-hr incubations with 75 mug/ml carbon black (Printex 90) or 100 mug/ml quartz (SRM1878a) particles in the FE1...
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