Article
Enzymatic recognition of DNA damage induced by UVB-photosensitized titanium dioxide and biological consequences in Saccharomyces cerevisiae: evidence for oxidatively DNA damage generation.
Mutation research - 1 Jun 2010
Pinto A Viviana, Deodato Elder L, Cardoso Janine S, Oliveira Eliza F, Machado Sérgio L, Toma Helena K, Leitão Alvaro C, de Pádula Marcelo
Abstract excerpt
Although titanium dioxide (TiO(2)) has been considered to be biologically inert, finding use in cosmetics, paints and food colorants, recent reports have demonstrated that when TiO(2) is attained by UVA radiation oxidative genotoxic and cytotoxic effects are observed in living cells. However, data concerning TiO(2)-UVB association is poor, even if UVB radiation represents a major environmental carcinogen. Herein,...
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