Article
[Photosensitized DNA damage: mechanisms and clinical use].
Nihon rinsho. Japanese journal of clinical medicine - 1 Nov 1996
Ito K, Kawanishi S
Abstract excerpt
On the basis of our recent investigations by a DNA sequencing technique, mechanisms of photoinduced DNA damage in the presence of various endogenous molecules are summarized with special reference to UV carcinogenesis. In particular, riboflavin and pterin derivatives have been shown to induce DNA...
Topics
- 8-Hydroxy-2'-Deoxyguanosine
- Animals
- DNA Damage
- Deoxyguanosine
- Electron Transport
- Humans
- Mutation
- Neoplasms
- Photochemotherapy
- Pterins
- Riboflavin
- Sequence Analysis, DNA
- Ultraviolet Rays
- ras Proteins