Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

G-to-T Transversions and Small Tandem Base Deletions Are the Hallmark of Mutations Induced by Ultraviolet A Radiation in Mammalian Cells

29 May 2004

Abstract excerpt

Ultraviolet A (UVA) radiation received from the sun and from the widespread use of tanning beds by populations residing in areas of northern latitude represents a potential risk factor for human health. The genotoxic and cancer-causing effects of UVA have remained controversial. A mutagenic role for UVA based on DNA damage formation by reactive oxygen species as well as by generation of photoproducts such as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinogens and Genotoxicity Assessment
Share to Skin Protection and Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15209513
DOI: 10.1021/bi049761v

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

G-to-T Transversions and Small Tandem Base Deletions Are the Hallmark of Mutations Induced by Ultraviolet A Radiation in Mammalian CellsPMID 15209513Read ↗

Mutagenicity of ultraviolet A radiation in the lacI transgene in Big Blue mouse embryonic fibroblasts.Semantic proximity Read ↗

Mutations induced by ultraviolet light.Semantic proximity Read ↗

Wavelength dependence of ultraviolet radiation-induced DNA damage as determined by laser irradiation suggests that cyclobutane pyrimidine dimers are the principal DNA lesions produced by terrestrial sunlight.Semantic proximity Read ↗

Mechanisms of UV-induced mutations and skin cancerSemantic proximity Read ↗

UVA1 genotoxicity is mediated not by oxidative damage but by cyclobutane pyrimidine dimers in normal mouse skin.Semantic proximity Read ↗

C-->T transition mutations are not solely UVB-signature mutations, because they are also generated by UVA.Semantic proximity Read ↗

Riboflavin activated by ultraviolet A1 irradiation induces oxidative DNA damage-mediated mutations inhibited by vitamin C.Semantic proximity Read ↗

UVA induces C-->T transitions at methyl-CpG-associated dipyrimidine sites in mouse skin epidermis more frequently than UVB.Semantic proximity Read ↗

UVA Radiation, DNA Damage, and MelanomaSemantic proximity Read ↗

Short- and long-wave UV light (UVB and UVA) induce similar mutations in human skin cells.Semantic proximity Read ↗

Cyclobutane pyrimidine dimers are predominant DNA lesions in whole human skin exposed to UVA radiationSemantic proximity Read ↗

The mechanisms of UV mutagenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.