Article
Association of AKT1 gene polymorphisms with risk of schizophrenia and with response to antipsychotics in the Chinese population.
The Journal of clinical psychiatry - 1 Sept 2007
Xu Ming-Qing, Xing Qing-He, Zheng Yong-Lan, Li Sheng, Gao Jian-Jun, He Guang, Guo Ting-Wei, Feng Guo-Yin, Xu Feng, He Lin
Abstract excerpt
BACKGROUND: A number of studies have pointed to the involvement of AKT signaling pathways in the etiology of schizophrenia. The purpose of this study was to determine whether the AKT1 gene is involved in the etiology of schizophrenia and whether it affects therapeutic outcomes in the Chinese population. METHOD: Five single nucleotide polymorphisms (SNPs) were genotyped among 384 schizophrenic patients (DSM-IV...
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